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    Home / Central Data Catalog / MWI-MEIRU-TB-COMBINE-FINAL-2022-V01
central

TB cases (1974-2018) and controls (1998-2018) analytical dataset (Karonga)

Malawi
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Reference ID
MWI-MEIRU-TB-COMBINE-FINAL-2022-v01
Producer(s)
Mia Crampin, Estelle McLean
Collections
Karonga -District-wide Combined / Harmonized Datasets Karonga HDSS
Metadata
Documentation in PDF DDI/XML JSON
Created on
Nov 14, 2025
Last modified
Nov 15, 2025
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24426
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  • Study Description
  • Data Dictionary
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  • combined_tb_cases_controls_final

Data file: combined_tb_cases_controls_final

The interview data for TB cases from the 3 eras are appended together and merged to the 'tbcpu' file. This latter file is the results of an algorithm that goes through all the TB data and creates TB episodes and assigns them to a category of how likely the episode was actually TB (see documentation on tbcpu algorithm). Only episodes on the tbcpu file are kept so other questionnaire data are dropped. Questionnaire data on controls from the 3 eras are appended to the cases dataset. Existing variables are modified and new ones created using the data from the questionnaires and data on lab results, contacts, GPS coordinates and follow-up and outcomes which are merged in. In the variable labels (S) indicates that the variable is unchanged from the original source and (D) indicates that it is a 'derived' variable, often using more than one source variable. For both types information on where the data come from and how they are processed is found in the 'Recoding and Derivation' section

Cases: 12911
Variables: 394

Variables

ident
unique identifier of person linkable to other studies
case
whether person is a case or control (D)
typind
Type of control
hhcons
If eligible for TB household study: has the patient consented?
spstdy
In Spouse study (D)
imm_eu
In EU immunology study (D)
imm_g
In Gates immunology study (D)
stid
unique identifier of person not linkable to other studies
pvrstid
unique identifier of palm vein registration study
intdate
date of interview
annualfu
annual follow-up
version
version of form
outvers
Version of outcome form
informtid
unique identifier of informant linkable to other studies
informant
type of informant (D)
birth_date
Date of birth (D)
sex
Sex
notprivate
Impossible to ask marital history and pregnancy questions
marital
Marital status (D)
schlever
Ever been to school (D)
schltype
Highest schooling type (D)
schlstd
Highest schooling standard (D)
stayaway
Do you stay away from your usual household to attend school?
yearsaway
If yes [to staying away for school], how many years so far?
emp
Employment code
occ
Main occupation (D)
occgp
Categorised occupation variable (D)
emp_score
Categorised occ/emp variable (D)
ind
describe industry (if not in agriculture/ forestry):
trained
Did you formally train in this occupation?
empnum
How many people do you employ in your main occupation?
occqualany
Do you have a formal qualification for the work you do in your main occupation?
emphead
Employment code [of household head]
occhead
Main occuption of household head (D)
occgphead
Categorised occupation variable of household head (D)
emp_scoreh
Categorised occ/emp variable of household head (D)
occqualanyh
Does household head have a formal qualification for main occupation?
indhead
describe industry (if not in agriculture/ forestry) [of household head]
trainedh
Whether household head is formally trained in occupation (D)
empnumh
How many people does he/she employ in your main occupation? [household head]
mothvita
whether mother is still alive
mothdyr
year of mother's death (D)
mothdyrx
whether year of mother's death is an estimate (D)
fathvita
whether father is still alive
fathdyr
year of father's death (D)
fathdyrx
whether year of father's death is an estimate (D)
pretrttb
Ever treated for TB previously (D)
pretrtyear
Year previously treated for TB (D)
pretrtyearx
Whether year of past TB treatment is estimated (D)
pretrtpl
Where were you treated? [in the past for TB]
tbtype
Type of TB (from tbcpu combined file) (D)
tbcpu
Whether TB is confirmed, probably or unknown (from tbcpu combined file) (D)
mic_resH
Highest microscopy result (from tbcpu combined file) (D)
cultposever
at least one positive culture during episode (from tbcpu combined file) (D)
outcome_cpu
Outcome (from tbcpu combined file) (D)
starteps
Start of TB episode (from tbcpu combined file) (D)
fineps
End of TB episode (from tbcpu combined file) (D)
treatstartdate
Start date of treatment (D)
treatstartdatex
Whether treatstartdate is estimated (D)
illdate
Illness onset date (D)
illdatex
if illness onset date is an estimate (D)
certtime
Certainty of illness timing (D)
cough
Have you been coughing?
coughdate
Coughing onset date (D)
coughdatex
if coughing onset date is an estimate (D)
swgl
Have you had swollen glands?
swgldate
Date of onset of swollen glands (D)
swgldatex
whether onset date of swollen glands is an estimate (D)
firstdate
Date first seeing health practitioner for illness (D)
firstdatex
Whether firsthpdate is estimated (D)
practype
Which type of health practitioner did you go to first?
hcdate
if first traditional healer: When first go to a health centre/clinic/hospital?
hcdatex
Whether hcdate is estimated
suggestb
Who first suggested you might have TB?
howadmit
How were you referred to hospital?
bedridden
Have you at any point been bedridden with this illness?
tbtype1
Site of TB [1]
tbtype2
Site of TB [2]
tbtype3
Site of TB [3]
smeacult
Smear positivity
smeacult_old
Smear positivity (D)
mic_resD
Microscopy result at diagnosis (D)
mic_res2m
Microscopy result 2 months after diagnosis (D)
mic_resC
Microscopy result within 2 months of treatment completion (D)
cult_resD
Culture result at diagnosis (D)
cult_res2m
Culture result 2 months after diagnosis (D)
cult_resC
Culture result within 2 months of treatment completion (D)
drugres_s
Whether patient was resistant to streptomycin at treatment start (D)
drugres_i
Whether patient was resistant to isoniazid at treatment start (D)
drugres_r
Whether patient was resistant to rifampicin at treatment start (D)
drugres_e
Whether patient was resistant to ethambutol at treatment start (D)
drugres_p
Whether patient was resistant to pyrazinamide at treatment start (D)
drugres_c
Whether patient was resistant to ciprofloxacin at treatment start (D)
biopdate
Date of biopsy (D)
bioptissue
Tissue biopsied (D)
biopdisease
Disease identified through biopsy (D)
biopcertainty
Certainty of biopsy diagnosis (D)
xpert
Was Xpert MTB/RIF done?
indication
What was the indication for doing Xpert MTB/RIF?
mtb
What was the result of Xpert MTB?
rif
What was the result of Xpert RIF?
cxr
Was chest x-ray done?
cxrdiag
Was it diagnostic of TB?
lymphhis
If lymphnode TB only, is diagnosis confirmed by histology?
hbres
Hb result
ictres
ICT result
tbclin
Current TB treatment Centre
tidate
Date registered at current TB treatment centre
tbclin1
Treatment centre registered (at initially)
treatint
Anti-tuberculous treatment
trtstartpl
Place treatment started
regintest
Whether intensive phase drug regimen is estimated (D)
regcontest
Whether continuation phase drug regimen is estimated (D)
drugreg_int
drug regimen of intensive phase (D)
drugreg_cont
drug regimen of continuation phase (D)
mthreg_int
length of intensive phase estimated (D)
mthreg_cont
length of continuation phase estimated (D)
trtchng
Was treatment changed during intensive phase?
chtrtint_drugs
Treatment change in intensive phase (D)
trtchngrsn
If yes, why? [treatment change in intensive phase]
cptrtchng
Was treatment changed during continuation phase?
chtrtcont_drugs
Treatment change in continuation phase (D)
cpchngrsn
If yes, why? [treatment change in continuation phase]
idhdhse
unique identifier of head of household linkable to other studies
curhse
current house
curvil
Current village
curghhid
current ghhid (D)
crs
CRS member at time of interview (D)
crshse
CRSHSE id at time of interview (D)
curgpspl
GPS based on village or household (D)
curgpssdeg
current GPS coord (south degrees) (D)
curgpssmin
current GPS coord (south minute) (D)
curgpsedeg
current GPS coord (east degrees) (D)
curgpsemin
current GPS coord (east minutes) (D)
joindate
Date of joining/becoming head of current household (D)
joindatex
Whether date of joining current household is an estimate (D)
rsnjoin
Reason for joining
posn
Position in household
prevvil
Previous village (D)
othhh5yr
Have you lived in another household during the last five years?
previl1
Give the most recent: Previous household Village1
prefrdate1
Date started living in previous village 1 (D)
prefrdate1x
Whether date started living in previous village 1 is an estimate (D)
pretodate1
Date stopped living in previous village 1 (D)
pretodate1x
Whether date stopped living in previous village 1 is an estimate (D)
leaversn1
why did you leave? [previous village 1]
previl2
Give the most recent: Previous household Village2
prefrdate2
Date started living in previous village 1 (D)
prefrdate2x
Whether date started living in previous village 1 is an estimate (D)
pretodate2
Date stopped living in previous village 2 (D)
pretodate2x
Whether date stopped living in previous village 2 is an estimate (D)
leaversn2
why did you leave? [previous village 2]
previl3
Give the most recent: Previous household Village3
prefrdate3
Date started living in previous village 3 (D)
prefrdate3x
Whether date started living in previous village 3 is an estimate (D)
pretodate3
Date stopped living in previous village 3 (D)
pretodate3x
Whether date stopped living in previous village 3 is an estimate (D)
leaversn3
why did you leave? [previous village 3]
previl4
Give the most recent: Previous household Village4
prefrdate4
Date started living in previous village 4 (D)
prefrdate4x
Whether date started living in previous village 4 is an estimate (D)
pretodate4
Date stopped living in previous village 4 (D)
pretodate4x
Whether date stopped living in previous village 4 is an estimate (D)
leaversn4
why did you leave? [previous village 4]
illcurhse
living in (current household) when you became unwell with this illness?
illghhid1
ghhid of household1
illfrdate1
Start date of living in house where became ill (if not current house) (D)
illfrdate1x
Whether illhsefrdate1 is an estimate (D)
illtodate1
Stop date of living in house where became ill (if not current house) (D)
illtodate1x
Whether illhsetodate1 is an estimate (D)
illtovill1
If no: Which village living in when you became unwell?
illvrsn1
Why did you leave? [household where became ill, if not current house]
illothhh
Lived in another household for two weeks or more since you started coughing?
illghhid2
gghid of household2
illsleep2
in this household2 were you sleeping in the same room with anyone?
illfrdate2
Start date of living in house2 where became ill (if not current house) (D)
illfrdate2x
Whether illhsefrdate2 is an estimate (D)
illtodate2
When stopped living at household2 since started coughing
illtodate2x
if illtodate2 is an estimate
illtovill2
village2 since started coughing
illghhid3
gghid of household3
illsleep3
in this household3 were you sleeping in the same room with anyone?
illfromdate3
When started living at household3 since started coughing
illfromdate3x
if illfromdate3 is an estimate
illtodate3
When stopped living at household3 since started coughing
illtodate3x
if illtodate3 is an estimate
illtovill3
village3 since started coughing
clincon
Been to an ART clinic as a guardian to someone or as a patient?
clin1
If yes Clinic1 [ART]
firyr1
First year1 [attending ART clinic1]
lasyr1
Last year1 [attending ART clinic1]
clin2
If yes Clinic2 [ART]
firyr2
First year2 [attending ART clinic2]
lasyr2
Last year2 [attending ART clinic2]
famtrttb
Has anyone in your household or close family EVER been treated for TB?
knowtrttb
Do you know anyone else who has been treated for TB, WITHIN THE LAST 5 YEARS?
idcontac1
ident of contact [wide] (D)
idcontac2
ident of contact [wide] (D)
idcontac3
ident of contact [wide] (D)
idcontac4
ident of contact [wide] (D)
idcontac5
ident of contact [wide] (D)
cfamcont1
Family contact? [wide] (D)
cfamcont2
Family contact? [wide] (D)
cfamcont3
Family contact? [wide] (D)
cfamcont4
Family contact? [wide] (D)
cfamcont5
Family contact? [wide] (D)
ccontvil1
Village when ill [wide] (D)
ccontvil2
Village when ill [wide] (D)
ccontvil3
Village when ill [wide] (D)
ccontvil4
Village when ill [wide] (D)
ccontvil5
Village when ill [wide] (D)
ccontplace1
Where did contact occur? [wide] (D)
ccontplace2
Where did contact occur? [wide] (D)
ccontplace3
Where did contact occur? [wide] (D)
ccontplace4
Where did contact occur? [wide] (D)
ccontplace5
Where did contact occur? [wide] (D)
ctrtdate1
Date treatment started [date] [wide] (D)
ctrtdatex1
Whether trtdate is an estimate [wide] (D)
ctrtdate2
Date treatment started [date] [wide] (D)
ctrtdatex2
Whether trtdate is an estimate [wide] (D)
ctrtdate3
Date treatment started [date] [wide] (D)
ctrtdatex3
Whether trtdate is an estimate [wide] (D)
ctrtdate4
Date treatment started [date] [wide] (D)
ctrtdatex4
Whether trtdate is an estimate [wide] (D)
ctrtdate5
Date treatment started [date] [wide] (D)
ctrtdatex5
Whether trtdate is an estimate [wide] (D)
ctrtplace1
Place of treatment [wide] (D)
ctrtplace2
Place of treatment [wide] (D)
ctrtplace3
Place of treatment [wide] (D)
ctrtplace4
Place of treatment [wide] (D)
ctrtplace5
Place of treatment [wide] (D)
ccerttbcon1
Are you sure it was TB? [wide] (D)
ccerttbcon2
Are you sure it was TB? [wide] (D)
ccerttbcon3
Are you sure it was TB? [wide] (D)
ccerttbcon4
Are you sure it was TB? [wide] (D)
ccerttbcon5
Are you sure it was TB? [wide] (D)
cwardvisit1
Did you visit them on the TB ward? Did you act as guardian? [wide] (D)
cwardvisit2
Did you visit them on the TB ward? Did you act as guardian? [wide] (D)
cwardvisit3
Did you visit them on the TB ward? Did you act as guardian? [wide] (D)
cwardvisit4
Did you visit them on the TB ward? Did you act as guardian? [wide] (D)
cwardvisit5
Did you visit them on the TB ward? Did you act as guardian? [wide] (D)
crelship1
What relationship is this person to you [wide] (D)
crelship2
What relationship is this person to you [wide] (D)
crelship3
What relationship is this person to you [wide] (D)
crelship4
What relationship is this person to you [wide] (D)
crelship5
What relationship is this person to you [wide] (D)
ccontaccon1
Did you have contact with them while they were ill? [wide] (D)
ccontaccon2
Did you have contact with them while they were ill? [wide] (D)
ccontaccon3
Did you have contact with them while they were ill? [wide] (D)
ccontaccon4
Did you have contact with them while they were ill? [wide] (D)
ccontaccon5
Did you have contact with them while they were ill? [wide] (D)
ccough1
When you saw them, when they had TB Did this person have a cough? [wide] (D)
ccough2
When you saw them, when they had TB Did this person have a cough? [wide] (D)
ccough3
When you saw them, when they had TB Did this person have a cough? [wide] (D)
ccough4
When you saw them, when they had TB Did this person have a cough? [wide] (D)
ccough5
When you saw them, when they had TB Did this person have a cough? [wide] (D)
cnurseill1
Did you nurse this person while they were ill? [wide] (D)
cnurseill2
Did you nurse this person while they were ill? [wide] (D)
cnurseill3
Did you nurse this person while they were ill? [wide] (D)
cnurseill4
Did you nurse this person while they were ill? [wide] (D)
cnurseill5
Did you nurse this person while they were ill? [wide] (D)
chouseill1
Did you live in the same household as them while they were ill? [wide] (D)
chouseill2
Did you live in the same household as them while they were ill? [wide] (D)
chouseill3
Did you live in the same household as them while they were ill? [wide] (D)
chouseill4
Did you live in the same household as them while they were ill? [wide] (D)
chouseill5
Did you live in the same household as them while they were ill? [wide] (D)
csleepill1
Did you sleep in same room as this person while they were ill? [wide] (D)
csleepill2
Did you sleep in same room as this person while they were ill? [wide] (D)
csleepill3
Did you sleep in same room as this person while they were ill? [wide] (D)
csleepill4
Did you sleep in same room as this person while they were ill? [wide] (D)
csleepill5
Did you sleep in same room as this person while they were ill? [wide] (D)
ccontacind1
Was your contact with this person indoors? [wide] (D)
ccontacind2
Was your contact with this person indoors? [wide] (D)
ccontacind3
Was your contact with this person indoors? [wide] (D)
ccontacind4
Was your contact with this person indoors? [wide] (D)
ccontacind5
Was your contact with this person indoors? [wide] (D)
ccontaclong1
Was your contact with this person prolonged? [wide] (D)
ccontaclong2
Was your contact with this person prolonged? [wide] (D)
ccontaclong3
Was your contact with this person prolonged? [wide] (D)
ccontaclong4
Was your contact with this person prolonged? [wide] (D)
ccontaclong5
Was your contact with this person prolonged? [wide] (D)
ccontacdays1
On how many days did you see this person while they were ill? [wide] (D)
ccontacdays2
On how many days did you see this person while they were ill? [wide] (D)
ccontacdays3
On how many days did you see this person while they were ill? [wide] (D)
ccontacdays4
On how many days did you see this person while they were ill? [wide] (D)
ccontacdays5
On how many days did you see this person while they were ill? [wide] (D)
drinkalcoh
Have you ever drunk alcohol
drinkyears
If yes: For how many years have/did you drunk alcohol?
drinkstill
Do you still drink?
drinkstop
Year stopped drinking alcohol (D)
drinkstopx
Whether year of stopping drinking is estimated (D)
drinkfreq
How frequently do/did you drink alcohol?
smoketobac
Have you ever smoked tobacco? (this does not include snuff or chewing tobacco)
smokewhat
If yes, what did (or do) you smoke?
smokenocig
How many did/do you smoke each day?
smokeyears
For how many years have/did you smoke(d)?
smokestill
Do you still smoke?
smokestop
Year stopped smoking (D)
smokestopx
Whether year of stopping smoking is estimated (D)
cooking
Before you became ill, how often did you do the cooking?
Total: 394
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